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We achieved the direct visualisation of gene organisation in Trypanosoma brucei using fluorescent in situ hybridisation on extended nuclear DNA fibres. We demonstrated the repetitive nature of the tubulin gene cluster, which consists of up to 19 alpha- and beta-tubulin genes arranged in tandem repeats.

Type

Journal article

Journal

Chromosoma

Publication Date

09/1998

Volume

107

Pages

237 - 240

Keywords

Animals, Chromosomes, DNA, Protozoan, Genes, Protozoan, In Situ Hybridization, Fluorescence, Protozoan Proteins, Trypanosoma brucei brucei, Tubulin