Cookies on this website
We use cookies to ensure that we give you the best experience on our website. If you click 'Continue' we'll assume that you are happy to receive all cookies and you won't see this message again. Click 'Find out more' for information on how to change your cookie settings.

Using in vitro immunization, we have reconstructed three consecutive steps of an idiotype network to show that the nucleocapsid of Semliki Forest virus contains a specific 'receptor' for the cytoplasmic tail of the E2 spike glycoprotein. This interaction could be the basis for the highly selective inclusion of viral glycoproteins--and exclusion of host cell surface proteins--during virus budding.

Original publication

DOI

10.1038/336036a0

Type

Journal article

Journal

Nature

Publication Date

03/11/1988

Volume

336

Pages

36 - 42

Keywords

Antibodies, Monoclonal, Capsid, Epitopes, Immunoglobulin Idiotypes, Semliki forest virus, Viral Proteins