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Cognitive impairment is a core feature of schizophrenia. Evidence in this Journal suggests that disrupted circadian synchronisation of sleep-wake phases may be one cause. Circadian synchronisation depends on the external input of light-dark cues and the integrity of central nervous system circadian oscillators; these may represent new interventional targets to improve cognition.

Original publication

DOI

10.1192/bjp.bp.110.085068

Type

Journal article

Journal

Br J Psychiatry

Publication Date

04/2011

Volume

198

Pages

250 - 252

Keywords

Cognition Disorders, Female, Humans, Male, Schizophrenia, Schizophrenic Psychology, Sleep Disorders, Circadian Rhythm