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How do very large cells coordinate their entry into mitosis? A new study shows that the bistability of the Cdk/Cyclin system allows cells to generate either 'trigger waves' or 'sweep waves' that drive cells into mitosis in different ways with distinct consequences.

Original publication

DOI

10.1016/j.cub.2022.10.030

Type

Journal article

Journal

Curr Biol

Publication Date

21/11/2022

Volume

32

Pages

R1262 - R1264

Keywords

Mitosis, Cell Cycle, Cyclins, Cell Cycle Proteins, Cell Cycle Checkpoints