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There are many routes to exploiting tolerance processes to ensure long-term graft survival. Complete tolerance although attractive as a goal, may not be the most practical in the clinic. Instead simple and low-impact procedures that harness tolerance processes used in conjunction with low doses of immunosuppressive drugs may prove the most reliable and user-friendly of approaches.

Original publication

DOI

10.1098/rstb.2001.0841

Type

Journal article

Journal

Philos Trans R Soc Lond B Biol Sci

Publication Date

29/05/2001

Volume

356

Pages

659 - 663

Keywords

Animals, Antibodies, Monoclonal, Antigens, CD, Antigens, CD4, Antigens, CD8, Antigens, Neoplasm, Bone Marrow Transplantation, Glycoproteins, Graft Rejection, Graft vs Host Disease, Humans, Lymphocyte Depletion, Models, Immunological, Transplantation Tolerance