Cookies on this website

We use cookies to ensure that we give you the best experience on our website. If you click 'Accept all cookies' we'll assume that you are happy to receive all cookies and you won't see this message again. If you click 'Reject all non-essential cookies' only necessary cookies providing core functionality such as security, network management, and accessibility will be enabled. Click 'Find out more' for information on how to change your cookie settings.

The KATP channel provides a link between metabolism and electrical activity in numerous cell types. It can be reconstituted by coexpression of two subunits, a pore-forming inward rectifier K+ channel and a regulatory subunit, the sulfonylurea receptor. Site-directed mutagenesis of these subunits enables analysis of the complex regulation of KATP, channel activity by metabolism and therapeutic drugs.


Journal article


News in Physiological Sciences

Publication Date





255 - 262