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The termination of transcription of eukaryotic genes by RNA polymerase II, at first sight, appears to be a rather random process, with the heterogeneous transcripts produced being processed to generate their correct 3' ends. However, recent studies have revealed that specific termination or pause sites may influence the process. The mechanism of termination may even play a role in eukaryotic gene regulation.

Type

Journal article

Journal

Trends Biochem Sci

Publication Date

03/1989

Volume

14

Pages

105 - 110

Keywords

Eukaryotic Cells, RNA Polymerase II, Transcription, Genetic