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Sea squirts are simple invertebrate chordates. In this issue of Developmental Cell, Takatori et al. show nuclear migration within ascidian mesendodermal cells enables polarized localization of Not mRNA, which encodes a homeobox protein that distinguishes mesoderm from endoderm fates. The link between nuclear migration and mRNA localization suggests exciting parallels with protostomes.

Original publication

DOI

10.1016/j.devcel.2010.10.002

Type

Journal article

Journal

Dev Cell

Publication Date

19/10/2010

Volume

19

Pages

487 - 488