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We are currently in the midst of an exciting revolution in microscopy. In many ways, this has been happening for several decades, but it is the rate of development of new methods that has increased recently. The last few years have seen an impressive proliferation of new instruments for imaging at higher resolution, imaging single molecules and faster and more sensitive multidimensional live cell imaging. These include light sheet microscopy, stimulated emission depletion, structured illumination and live cell imaging on the OMX (optical microscopy experimental) platform. However, new probes and image analysis methods have also been crucial for the development of these revolutionary methods.

Original publication

DOI

10.1042/BST0371042

Type

Journal article

Journal

Biochem Soc Trans

Publication Date

10/2009

Volume

37

Pages

1042 - 1044

Keywords

Fluorescent Dyes, Image Enhancement, Light, Lighting, Microscopy, Optics and Photonics