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Nervous system cells defined in unprecedented detail

Research Highlights

The collaborating groups of Professor Stephen Goodwin and Professor Scott Waddell based in The Centre for Neural Circuits and Behaviour (CNCB) are shedding new light on what precisely constitutes a neuronal cell type.

How has COVID-19 Impacted on People's Vulnerability to Mental Illness and Depression?

Research Highlights

The Oxford University COSIE study (COvid-19, Social Isolation and Emotion) is an online study which asked people about their experiences during the coronavirus lockdown in late April 2020, while also using objective tests of psychological function to measure vulnerability to mental illness such as depression.

New Oxford University Research Study Will Track What Helps or Harms Adolescents’ Mental Health during the COVID-19 Crisis

Research Highlights

A new research survey launches today from experts at the University of Oxford along with collaborators from the Universities of Cambridge, Glasgow, and New South Wales. It will track adolescents’ mental health during the COVID-19 crisis to find out what promotes or hinders their resilience.

Nuffield Early Language Intervention Found Highly Effective in Large-Scale Trial

Research Highlights

The Nuffield Early Language Intervention catch-up programme developed by Maggie Snowling and Charles Hulme – has been found to give a 3+ month boost to the language skills of 4-5 year-olds who are falling behind.

Let them know you care – social disconnection worsens mental health after a loss

Research Highlights

Keeping grief hidden can be a survival strategy after suffering a bereavement. However, new research released today shows that the social disconnection caused by concealing feelings of loss can increase psychological distress.

Studying the impact of COVID-19 on epilepsy

Research Highlights

NDCN researchers lead a global study based on analysing survey data

Using MRI to investigate the effect of COVID-19 on the brain

Research Highlights

A team of NDCN neuroimaging researchers will lead this study, which has received a grant from the University of Oxford's COVID-19 Research Response Fund.

Natural mood regulation low or even absent in people with depression: how will lockdown affect this?

Research Highlights

Supporting natural mood regulation is a new direct target for developing novel treatments, optimising existing ones and integrating drug and psychotherapies to reduce the disease burden of depression, according to new research, published in JAMA Psychiatry, from the Department of Psychiatry, University of Oxford.

A new blood-based test to help predict Parkinson’s disease

Research Highlights

Research carried out by George Tofaris and his team has led to the development of a new way to test for Parkinson’s disease before the main symptoms occur. This could allow clinicians to identify patients who would benefit from precision therapies that are currently at clinical trial stage.

Lifetime suicide risk factors identified

Research Highlights

A new review by researchers in the Department of Psychiatry of previous studies into suicide worldwide has highlighted the effects of individual and environmental risk factors over a lifetime.

Oxford is joint top recruiter to drug-resitant epilepsy study

Research Highlights Strategic Developments

The Oxford Epilepsy Research Group is at the forefront of some potentially ground-breaking work with patients who have drug-resistant epilepsy. Epilepsy affects over 50 million people worldwide and nearly one in three people with epilepsy are resistant to current drugs.

Advances made in understanding how eye movements are affected by medication in Parkinson's

Research Highlights

The Neurometrology Group has published findings from its OxQUIP study looking at how eye movements are affected by medication in Parkinson's.

How our brains remember things depends upon how we learn them

Research Highlights

Oxford University researchers have discovered that learnt knowledge is stored in different brain circuits depending on how we acquire it.

Dementias Platform UK 5 year celebration event

Events Research Highlights

At the five-year celebration event, scientists and health study volunteers from across the DPUK partnership came together to launch one of the world’s most in-depth study's into preclinical Alzheimer’s disease - one of the most important outcomes from DPUK's work to transform dementia research infrastructure in the UK.

Smartphone test predicts how symptoms develop in Parkinson’s

Research Highlights

Researchers from the Nuffield Dept of Clinical Neurosciences have found that a simple test carried out on a smartphone can help to predict future change in people in the early stages of Parkinson’s.

Close Monitoring Essential to Ensure Safety of Ketamine for Depression

Research Highlights

Patients, carers and advocates say better evidence is needed on the safety of ketamine for depression after long-term use, and that those prescribed it must be closely monitored.

Virtual Reality Could Transform Psychological Therapy in the NHS

Research Highlights Strategic Developments

A new clinical trial is testing a virtual reality (VR) based psychological therapy for people with severe mental health difficulties. gameChange is the largest ever clinical trial of virtual reality for a mental health disorder. Automated delivery of therapy using VR has potential to transform NHS provision of psychological therapy.

Clinical Guidelines for Antidepressant Dosage Must Reflect the Evidence

Research Highlights

New analysis shows the lower range of the licensed dose of the most commonly used second-generation antidepressants achieves the optimal balance between efficacy, tolerability and acceptability in the acute treatment of adults with major depression.

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