The putative lithium-mimetic ebselen reduces impulsivity in rodent models.
Barkus C. et al, (2018), J Psychopharmacol, 32, 1018 - 1026
Trisomy of human chromosome 21 enhances amyloid-β deposition independently of an extra copy of APP.
Wiseman FK. et al, (2018), Brain
Pharmacological evidence that 5-HT2C receptor blockade selectively improves decision making when rewards are paired with audiovisual cues in a rat gambling task.
Adams WK. et al, (2017), Psychopharmacology (Berl), 234, 3091 - 3104
The group II metabotropic glutamate receptor agonist LY354740 and the D2 receptor antagonist haloperidol reduce locomotor hyperactivity but fail to rescue spatial working memory in GluA1 knockout mice.
Boerner T. et al, (2017), Eur J Neurosci, 45, 912 - 921
Genotype-Dependent Effects of COMT Inhibition on Cognitive Function in a Highly Specific, Novel Mouse Model of Altered COMT Activity.
Barkus C. et al, (2016), Neuropsychopharmacology, 41, 3060 - 3069
Knockout of NMDA-receptors from parvalbumin interneurons sensitizes to schizophrenia-related deficits induced by MK-801.
Bygrave AM. et al, (2016), Transl Psychiatry, 6
Searching for cognitive enhancement in the Morris water maze: better and worse performance in D-amino acid oxidase knockout (Dao(-/-)) mice.
Pritchett D. et al, (2016), Eur J Neurosci, 43, 979 - 989
SERT and uncertainty: serotonin transporter expression influences information processing biases for ambiguous aversive cues in mice.
McHugh SB. et al, (2015), Genes Brain Behav, 14, 330 - 336
Reduced sensitivity to both positive and negative reinforcement in mice over-expressing the 5-hydroxytryptamine transporter.
Line SJ. et al, (2014), Eur J Neurosci, 40, 3735 - 3745
What causes aberrant salience in schizophrenia? A role for impaired short-term habituation and the GRIA1 (GluA1) AMPA receptor subunit.
Barkus C. et al, (2014), Mol Psychiatry, 19, 1060 - 1070
Aversive prediction error signals in the amygdala.
McHugh SB. et al, (2014), J Neurosci, 34, 9024 - 9033
Variation in serotonin transporter expression modulates fear-evoked hemodynamic responses and theta-frequency neuronal oscillations in the amygdala.
Barkus C. et al, (2014), Biol Psychiatry, 75, 901 - 908
Hippocampal lesions can enhance discrimination learning despite normal sensitivity to interference from incidental information.
Sanderson DJ. et al, (2012), Hippocampus, 22, 1553 - 1566
Hippocampal lesions can enhance discrimination learning despite normal sensitivity to interference from incidental information
Sanderson DJ. et al, (2012), Hippocampus, 22, 1553 - 1566
GluN1 hypomorph mice exhibit wide-ranging behavioral alterations
Barkus C. et al, (2012), Genes, Brain and Behavior, 11, 342 - 351
GluN1 hypomorph mice exhibit wide-ranging behavioral alterations.
Barkus C. et al, (2012), Genes Brain Behav, 11, 342 - 351
Do GluA1 knockout mice exhibit behavioral abnormalities relevant to the negative or cognitive symptoms of schizophrenia and schizoaffective disorder?
Barkus C. et al, (2012), Neuropharmacology, 62, 1263 - 1272
Do GluA1 knockout mice exhibit behavioral abnormalities relevant to the negative or cognitive symptoms of schizophrenia and schizoaffective disorder?
Barkus C. et al, (2012), Neuropharmacology, 62, 1263 - 1272
Systemic inflammation induces acute working memory deficits in the primed brain: relevance for delirium.
Murray C. et al, (2012), Neurobiol Aging, 33, 603 - 616.e3