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The MAT alpha 2 protein of budding yeast represses a set of genes; if the MATa1 protein is also present, a further set of genes is repressed. DNA sequence comparisons reveal a 20-base pair 'operator' sequence that is present in genes repressed by a1/alpha 2. A related, but distinct, sequence is found in genes repressed by alpha 2 alone.

Type

Journal article

Journal

Nature

Publication Date

18/04/1985

Volume

314

Pages

598 - 603

Keywords

Base Sequence, DNA, Fungal, Gene Expression Regulation, Genes, Fungal, Mating Factor, Peptides, Promoter Regions, Genetic, Repressor Proteins, Saccharomyces cerevisiae, Transcription, Genetic