Cookies on this website
We use cookies to ensure that we give you the best experience on our website. If you click 'Continue' we'll assume that you are happy to receive all cookies and you won't see this message again. Click 'Find out more' for information on how to change your cookie settings.

Southern hybridization suggests that the zebrafish genome contains multiple zinc-finger genes related to the putative mouse developmental genes, Krox-20 and Krox-24. The polymerase chain reaction was employed to amplify and clone the zinc-finger regions of genes related to Krox-20, from two fish species and, for comparison, mouse, hamster and fox. DNA sequence analyses suggest that the genes cloned include the guppy homologue of Krox-20 and the zebrafish homologue of Krox-24, and that these genes diverged prior to the separation of the lineages leading to teleosts and to mammals.

Type

Journal article

Journal

Biochem Biophys Res Commun

Publication Date

30/09/1991

Volume

179

Pages

1220 - 1224

Keywords

Amino Acid Sequence, Animals, Base Sequence, Blotting, Southern, Cell Line, DNA, Fishes, Genes, Liver, Mice, Mice, Inbred DBA, Molecular Sequence Data, Oligodeoxyribonucleotides, Poecilia, Polymerase Chain Reaction, Sequence Homology, Nucleic Acid, Zebrafish, Zinc Fingers