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An NAD(P)H quinone reductase isolated from Walker rat 256 carcinoma cells has been crystallized in a form suitable for high-resolution structural analysis. The crystals belong to orthorhombic space group P2(1)2(1)2(1) with cell parameters a = 168.15 A, b = 105.09 A and c = 67.38 A and contain four monomeric or two dimeric enzyme molecules per asymmetric unit. Diffraction extends beyond 2.3 A resolution.

Original publication

DOI

10.1016/0022-2836(89)90233-7

Type

Journal article

Journal

J Mol Biol

Publication Date

05/02/1989

Volume

205

Pages

623 - 624

Keywords

Animals, Cell Line, NAD(P)H Dehydrogenase (Quinone), Quinone Reductases, Rats, Tumor Cells, Cultured, X-Ray Diffraction