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2001 was the year of the human genome, but the new information has had little immediate impact on the field of nuclear structure. Rather, functional studies - especially on transcription - are leading us to a better understanding of how genomes might organise themselves into structures we call nuclei.


Journal article


Curr Opin Cell Biol

Publication Date





780 - 785


Animals, Cell Nucleus, Chromatin, DNA Repair, DNA Replication, Humans, Models, Genetic, RNA Transport, Recombination, Genetic, Transcription, Genetic