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Stroke is a major cause of death and disability worldwide. Without improvements in prevention, the burden will increase during the next 20 years because of the ageing population, especially in developing countries. Major advances have occurred in secondary prevention during the past three decades, which demonstrate the broader potential to prevent stroke. We review the main medical treatments that should be considered for most patients with transient ischaemic attack or ischaemic stroke in the acute phase and the long term, and draw attention to recent developments.

Original publication

DOI

10.1016/S0140-6736(11)60516-3

Type

Journal article

Journal

Lancet

Publication Date

14/05/2011

Volume

377

Pages

1681 - 1692

Keywords

Acute Disease, Anticoagulants, Antihypertensive Agents, Atrial Fibrillation, Brain Ischemia, Cardiovascular Agents, Cholesterol, HDL, Cholesterol, LDL, Chronic Disease, Developing Countries, Dyslipidemias, Fibrinolytic Agents, Humans, Hypertension, Hypolipidemic Agents, Ischemic Attack, Transient, Predictive Value of Tests, Prognosis, Risk Assessment, Risk Factors, Secondary Prevention, Stroke, Time Factors, Triage