Cookies on this website
We use cookies to ensure that we give you the best experience on our website. If you click 'Continue' we'll assume that you are happy to receive all cookies and you won't see this message again. Click 'Find out more' for information on how to change your cookie settings.

Meta-analysis led by Dr Andrea Cipriani (Department of Psychiatry) of 522 trials includes the largest amount of unpublished data to date, and finds that antidepressants are more effective than placebo for short-term treatment of acute depression in adults.

A major study comparing 21 commonly used antidepressants concludes that all are more effective than placebo for the short-term treatment of acute depression in adults, with effectiveness ranging from small to moderate for different drugs.

The international study, published in The Lancet, is a network meta-analysis of 522 double-blind, randomised controlled trials comprising a total of 116477 participants. The study includes the largest amount of unpublished data to date, and all the data from the study have been made freely available online.

Find out more (Department of Psychiatry website)

Similar stories

100 Women of Oxford Medical Sciences

Awards and Honours Events

MSD launches project to celebrate 100 years since women were admitted as full members of the University.

Teenage Brain Workshop

Events Public Engagement

A new workshop aimed at young people to inspire them to learn more about the science of the brain has been designed as part of a large Wellcome Trust funded research programme.

Dementias Platform UK 5 year celebration event

Events Research Highlights

At the five-year celebration event, scientists and health study volunteers from across the DPUK partnership came together to launch one of the world’s most in-depth study's into preclinical Alzheimer’s disease - one of the most important outcomes from DPUK's work to transform dementia research infrastructure in the UK.

Oxford Short Course in Experimental Medicine for Mental Health - OxCEMM

Events Strategic Developments

This new course ran for the first time in January 2019, with an engaging and thought-provoking programme of talks, tours of facilities and group discussions. Feedback from participants was uniformly excellent. Applications for the January 2020 course opened on 15th August 2019.

Dementias Platform UK datathon - understanding origins of dementia using machine learning

Events Strategic Developments

Using machine learning (AI) techniques to analyse complex cohort data, a group of researchers uncovered hidden patterns in cohort data that might identify those at risk of developing dementia, or indicate promising areas for research into treatments.

Illuminating the brain – Neuroscientist Dr Karl Deisseroth

Events

Dr Karl Deisseroth, D.H. Chen Professor of Bioengineering and of Psychiatry and Behavioural Sciences, was in Oxford last week for the Kyoto Prize at Oxford.