Vanessa Raymont

MBChB MSc MRCPsych

Senior Clinical Researcher, R&D Director Oxford Health NHS Foundation Trust

Honorary Senior Clinical Research Fellow, Centre of Dementia Prevention, University of Edinburgh
Honorary Consultant Psychiatrist

My clinical and research interests are in traumatic brain injury, and memory disorders and dementia, as well as clinical trials in cognitive impairment, having worked for over 20 years in clinical trials in the UK and US.

I am currently the Principal Investigator for the New Therapeutics in Alzheimer’s Disease (NTAD), Brains for Dementia Research (BDR) and 7Tesla MRI Scanning in Alzheimer’s disease and Frontotemporal Lobar Degeneration studies and Chief Investigator on the Deep and Frequent Phenotyping (DFP) study and a NHIR-funded study assessing the use of sertraline to prevent post-head injury depression. I am co-lead for the Clinical Trials section of Oxford Translational Neuroscience and Dementia Research Group and NIHR Dementia and Mental Health Lead for the Thames Valley and South Midlands Clinical Research Network. I am an associate director of Dementia Platforms UK, and workstream lead for the Trials Delivery Framework. I serve as a Commissioner for the Commission on Human Medicines.

Recent publications

Patient attitudes towards remote memory clinic assessment.
Journal article

Blane J. et al, (2021), Alzheimers Dement, 17 Suppl 11
Genetic Therapies for Alzheimer's Disease: A Scoping Review.
Journal article

Lennon MJ. et al, (2021), J Alzheimers Dis
A systematic review and meta-analysis of gestational diabetes mellitus and mental health among BAME populations.
Journal article

Delanerolle G. et al, (2021), EClinicalMedicine, 38
Safety and efficacy of pioglitazone for the delay of cognitive impairment in people at risk of Alzheimer's disease (TOMMORROW): a prognostic biomarker study and a phase 3, randomised, double-blind, placebo-controlled trial
Journal article

Burns DK. et al, (2021), The Lancet Neurology, 20, 537 - 547
An evaluation of the mental health impact of SARS-CoV-2 on patients, general public and healthcare professionals: A systematic review and meta-analysis.
Journal article

Phiri P. et al, (2021), EClinicalMedicine, 34
History for some or lesson for all? A systematic review and meta-analysis on the immediate and long-term mental health impact of the 2002-2003 Severe Acute Respiratory Syndrome (SARS) outbreak
Journal article

Chau S. et al, (2021), BMC Public Health
Rapid commentary: Ethical implications for clinical trialists and patients associated with COVID-19 research.
Journal article

Delanerolle G. et al, (2021), World J Psychiatry, 11, 58 - 62
The association between anxiety disorders and hippocampal volume in older adults.
Journal article

Baksh RA. et al, (2021), Psychol Aging, 36, 288 - 297
Women in science: achievements and ambitions
Journal article

Delanerolle G. et al, (2021), British Journal of Neuroscience Nursing, 17, 13 - 16
A systematic review and meta-analysis of the Endometriosis and Mental-Health Sequelae; The ELEMI Project.
Journal article

Delanerolle G. et al, (2021), Womens Health (Lond), 17
Artificial intelligence: A rapid case for advancement in the personalization of Gynaecology/Obstetric and Mental Health care.
Journal article

Delanerolle G. et al, (2021), Womens Health (Lond), 17
Bilingualism: A Global Public Health Strategy for Healthy Cognitive Aging.
Journal article

Mendis SB. et al, (2021), Front Neurol, 12
A SYSTEMATIC REVIEW TO IDENTIFY AND ASSESS THE MENTAL HEALTH SEQUALAE AMONGST WOMEN WITH ENDOMETRIOSIS WITH OR WITHOUT CHRONIC PELVIC PAIN (THE ELEMI PROJECT)
Conference paper

Hapangama D. et al, (2020), INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER, 30, A52 - A53
Prediction of Alzheimer's disease biomarker status defined by the 'ATN framework' among cognitively healthy individuals: results from the EPAD longitudinal cohort study.
Journal article

Calvin CM. et al, (2020), Alzheimers Res Ther, 12
What do we know about the risks of developing dementia after traumatic brain injury?
Journal article

Raymont V. and Thayanandan T., (2020), Minerva Med
Left rostrolateral prefrontal cortex lesions reduce suicidal ideation in penetrating traumatic brain injury.
Journal article

Pardini M. et al, (2020), CNS Spectr, 25, 24 - 31
Patients with Lesions to Left Prefrontal Cortex (BA 9 and BA 10) Have Less Entrenched Beliefs and Are More Skeptical Reasoners.
Journal article

Goel V. et al, (2019), J Cogn Neurosci, 31, 1674 - 1688
Partnership in practice: an innovative Brain Health Centre
Conference paper

O'DONOGHUE M. et al, (2019)
Deep and Frequent Phenotyping study protocol: an observational study in prodromal Alzheimer's disease.
Journal article

Koychev I. et al, (2019), BMJ Open, 9
Dopamine D2/D3 receptor abnormalities after traumatic brain injury and their relationship to post-traumatic depression.
Journal article

Jolly AE. et al, (2019), Neuroimage Clin, 24
Differential roles of polar orbital prefrontal cortex and parietal lobes in logical reasoning with neutral and negative emotional content.
Journal article

Eimontaite I. et al, (2018), Neuropsychologia, 119, 320 - 329
Interventions to enhance coping after traumatic brain injury: A systematic review
Journal article

Mueller C. et al, (2018), International Journal of Therapy and Rehabilitation, 25, 107 - 119
Remission of Gilles de la Tourette Syndrome after Heat-Induced Dehydration.
Journal article

Robert Brašić J. et al, (2018), Int J Phys Med Rehabil, 6
A preliminary report about the psychological effects of dopamine on people with the syndrome of Gilles de la Tourette. report about the psychological effects of dopamine on people with the syndrome of Gilles de la Tourette
Conference paper

Brasic J. et al, (2017), JOURNAL OF NUCLEAR MEDICINE, 58
Lesions to polar/orbital prefrontal cortex selectively impair reasoning about emotional material.
Journal article

Goel V. et al, (2017), Neuropsychologia, 99, 236 - 245
'Attending to the wound and the person' - patients' experiences and expectations of a newly established traumatic brain injury clinic.
Journal article

Mueller C. et al, (2017), Brain Inj, 31, 1863 - 1870
Suicidal thoughts and emotion competence.
Journal article

Paradiso S. et al, (2016), J Clin Exp Neuropsychol, 38, 887 - 899
A randomised controlled trial of calcium channel blockade (CCB) with Amlodipine For the treatment oF subcortical ischaEmic vasCular demenTia (AFFECT): study protocol.
Journal article

Greenan C. et al, (2016), Trials, 17
Brain Regions Associated With Internalizing and Externalizing Psychiatric Symptoms in Patients With Penetrating Traumatic Brain Injury.
Journal article

Huey ED. et al, (2016), J Neuropsychiatry Clin Neurosci, 28, 104 - 111
Anhedonia in combat veterans with penetrating head injury.
Journal article

Lewis JD. et al, (2015), Brain Imaging Behav, 9, 456 - 460
ITI-007 demonstrates brain occupancy at serotonin 5-HT₂A and dopamine D₂ receptors and serotonin transporters using positron emission tomography in healthy volunteers.
Journal article

Davis RE. et al, (2015), Psychopharmacology (Berl), 232, 2863 - 2872
Areas of Brain Damage Underlying Increased Reports of Behavioral Disinhibition.
Journal article

Knutson KM. et al, (2015), J Neuropsychiatry Clin Neurosci, 27, 193 - 198
Aggression, DRD1 polymorphism, and lesion location in penetrating traumatic brain injury.
Journal article

Pardini M. et al, (2014), CNS Spectr, 19, 382 - 390
Functional recovery after moderate/severe traumatic brain injury: a role for cognitive reserve?
Journal article

Schneider EB. et al, (2014), Neurology, 82, 1636 - 1642
Neural correlates of apathy revealed by lesion mapping in participants with traumatic brain injuries.
Journal article

Knutson KM. et al, (2014), Hum Brain Mapp, 35, 943 - 953
Erratum: 11C-RO5013853: A New PET radioligand for the glycine transporter TYPE 1 (Neuropsychopharmacology 35 (S297-S408) DOI: 10.1038/npp.2010.218)
Journal article

Wong D. et al, (2014), Neuropsychopharmacology, 39
PET imaging of endocannabinoid system
Chapter

Horti AG. et al, (2014), PET and SPECT of Neurobiological Systems, 249 - 319
Decision-making capacity for treatment in psychiatric and medical in-patients: cross-sectional, comparative study.
Journal article

Owen GS. et al, (2013), Br J Psychiatry, 203, 461 - 467
A voxel-based lesion study on facial emotion recognition after penetrating brain injury.
Journal article

Dal Monte O. et al, (2013), Soc Cogn Affect Neurosci, 8, 632 - 639
Characterization of [11C]RO5013853, a novel PET tracer for the glycine transporter type 1 (GlyT1) in humans.
Journal article

Wong DF. et al, (2013), Neuroimage, 75, 282 - 290
Mental paper folding performance following penetrating traumatic brain injury in combat veterans: a lesion mapping study.
Journal article

Glass L. et al, (2013), Cereb Cortex, 23, 1663 - 1672
Reduced dopamine blockade in the basal ganglia in obsessive-compulsive disorder
Conference paper

Brasic J. et al, (2013), JOURNAL OF NUCLEAR MEDICINE, 54
Cognition and amyloid load in Alzheimer disease imaged with florbetapir F 18(AV-45) positron emission tomography.
Journal article

Rosenberg PB. et al, (2013), Am J Geriatr Psychiatry, 21, 272 - 278
Injured brain regions associated with anxiety in Vietnam veterans.
Journal article

Knutson KM. et al, (2013), Neuropsychologia, 51, 686 - 694
Semi-automated trajectory analysis of deep ballistic penetrating brain injury.
Journal article

Folio L. et al, (2013), Mil Med, 178, 338 - 345
Glycine transporter type 1 occupancy by bitopertin: a positron emission tomography study in healthy volunteers.
Journal article

Martin-Facklam M. et al, (2013), Neuropsychopharmacology, 38, 504 - 512
Transitive inference reasoning is impaired by focal lesions in parietal cortex rather than rostrolateral prefrontal cortex.
Journal article

Waechter RL. et al, (2013), Neuropsychologia, 51, 464 - 471
New approaches to the synthesis of strapped porphyrin containing bipyridinium [2]rotaxanes
Journal article

Raymont V. et al, (2013), New Journal of Chemistry, 37, 893 - 900
Dopamine release and serotonin interactions in Tourette's syndrome: new relations to obsessive compulsive disorder
Conference paper

Wong DF. et al, (2012), JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM, 32, S96 - S97
Effects of amphetamine-induced dopamine release and raclopride-induced dopamine blockade on psychiatric symptoms and tics of subjects with and without Gilles de la Tourette syndrome
Conference paper

Brasic JR. et al, (2012), JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM, 32, S92 - S92
Correlation of psychiatric symptoms and tics with amphetamine-induced dopamine release (DAR) in the striata of people with Gilles de la Tourette syndrome (TS) and obsessive-compulsive disorder (OCD)
Conference paper

Brasic J. et al, (2012), JOURNAL OF NUCLEAR MEDICINE, 53
Imaging biomarkers for the glycine transporter type 1
Conference paper

Wong D. et al, (2012), JOURNAL OF NUCLEAR MEDICINE, 53
Cannabinoid Receptor Subtype 1 (CB1) Distribution Correlates with Neuropsychiatric Ratings
Conference paper

Wong DF. et al, (2012), BIOLOGICAL PSYCHIATRY, 71, 258S - 258S
Positron emission tomography experience with 2-[¹⁸F]fluoro-3-(2(S)-azetidinylmethoxy)pyridine (2-[¹⁸F]FA) in the living human brain of smokers with paranoid schizophrenia.
Journal article

Brašić JR. et al, (2012), Synapse, 66, 352 - 368
Fatty-acid amide hydrolase polymorphisms and post-traumatic stress disorder after penetrating brain injury.
Journal article

Pardini M. et al, (2012), Transl Psychiatry, 2
Gustatory cortical lesions affect motivation for snack foods.
Journal article

Knutson KM. et al, (2012), Cogn Neurosci, 3, 131 - 138
Cannabinoid receptor subtype 1 (CB1) distribution and neuropsychiatric ratings
Conference paper

Wong D. et al, (2011), JOURNAL OF NUCLEAR MEDICINE, 52
Differences in dopamine release in Tourette's syndrome and obsessive-compulsive disorder
Conference paper

Wong D. et al, (2011), JOURNAL OF NUCLEAR MEDICINE, 52
Partial remission of Gilles de la Tourette syndrome in a 24-year-old man after heat-induced dehydration
Conference paper

Brasic JR. et al, (2011), MOVEMENT DISORDERS, 26, S368 - S368
Prefrontal cortex lesions and MAO-A modulate aggression in penetrating traumatic brain injury.
Journal article

Pardini M. et al, (2011), Neurology, 76, 1038 - 1045
The role of the Met66 brain-derived neurotrophic factor allele in the recovery of executive functioning after combat-related traumatic brain injury.
Journal article

Krueger F. et al, (2011), J Neurosci, 31, 598 - 606
"Studying injured minds" - the Vietnam head injury study and 40 years of brain injury research.
Journal article

Raymont V. et al, (2011), Front Neurol, 2
BDNF polymorphism predicts general intelligence after penetrating traumatic brain injury.
Journal article

Rostami E. et al, (2011), PLoS One, 6
Quantification of cerebral cannabinoid receptors subtype 1 (CB1) in healthy subjects and schizophrenia by the novel PET radioligand [11C]OMAR.
Journal article

Wong DF. et al, (2010), Neuroimage, 52, 1505 - 1513
Cannaboid CB1 receptor imaging in vivo in schizophrenia by positron emission tomography
Conference paper

Wong DF. et al, (2010), NEUROIMAGE, 52, S11 - S12
Evaluation of occupancy of cannabinoid CB1 receptors by a novel antagonist drug with [11C]OMAR and PET
Conference paper

Wong DF. et al, (2010), NEUROIMAGE, 52, S64 - S64
Exploration of function-neurotransmitter correlation using binding potential maps of multiple receptor systems of healthy human volunteers
Conference paper

Kuwabara H. et al, (2010), NEUROIMAGE, 52, S185 - S185
Correlates of posttraumatic epilepsy 35 years following combat brain injury.
Journal article

Raymont V. et al, (2010), Neurology, 75, 224 - 229
In vivo imaging of amyloid deposition in Alzheimer disease using the radioligand 18F-AV-45 (florbetapir [corrected] F 18).
Journal article

Wong DF. et al, (2010), J Nucl Med, 51, 913 - 920
STRIATAL DOPAMINE RELEASE IS COMPROMISED IN ALCOHOL-DEPENDENT SUBJECTS
Conference paper

Wong DF. et al, (2010), ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH, 34, 256A - 256A
Identification of region specific occupancy of mu-opioid receptors by fixed dose naltrexone in alcohol dependent subjects
Conference paper

Kuwabara H. et al, (2010), JOURNAL OF NUCLEAR MEDICINE, 51
Quantification of cerebral cannabinoid receptors subtype 1 (CB1) in healthy subjects and schizophrenia by the novel PET radioligand [C-11]OMAR
Conference paper

Wong D. et al, (2010), JOURNAL OF NUCLEAR MEDICINE, 51
Ventromedial prefrontal cortex modulates fatigue after penetrating traumatic brain injury.
Journal article

Pardini M. et al, (2010), Neurology, 74, 749 - 754
AN IN VIVO POSITRON EMISSION TOMOGRAPHY STUDY OF THE CB1 OCCUPANCY BY AVE1625 USING [C-11]-JHU75528 IN HEALTHY SUBJECTS AND IN PATIENTS WITH SCHIZOPHRENIA.
Conference paper

Ming JE. et al, (2010), CLINICAL PHARMACOLOGY & THERAPEUTICS, 87, S67 - S67
The neural bases of key competencies of emotional intelligence.
Journal article

Krueger F. et al, (2009), Proc Natl Acad Sci U S A, 106, 22486 - 22491
Dissociable effects of prefrontal and anterior temporal cortical lesions on stereotypical gender attitudes.
Journal article

Gozzi M. et al, (2009), Neuropsychologia, 47, 2125 - 2132
PET IMAGING OF CANNABINOID RECEPTORS IN SCHIZOPHRENIA
Conference paper

Wong DF. et al, (2009), SCHIZOPHRENIA BULLETIN, 35, 172 - 172
Distinct regions of prefrontal cortex mediate resistance and vulnerability to depression.
Journal article

Koenigs M. et al, (2008), J Neurosci, 28, 12341 - 12348
Examining ventral and dorsal prefrontal function in bipolar disorder: a functional magnetic resonance imaging study.
Journal article

Frangou S. et al, (2008), Eur Psychiatry, 23, 300 - 308
Demographic, structural and genetic predictors of late cognitive decline after penetrating head injury.
Journal article

Raymont V. et al, (2008), Brain, 131, 543 - 558
Focal brain damage protects against post-traumatic stress disorder in combat veterans.
Journal article

Koenigs M. et al, (2008), Nat Neurosci, 11, 232 - 237
PET Imaging of cannabinoid CB1 type receptors in healthy humans and patients with schizophrenia using [C-11]OMAR
Conference paper

Wong DF. et al, (2008), NEUROIMAGE, 41, T51 - T51
User-friendly software for the analysis of brain lesions (ABLe).
Journal article

Solomon J. et al, (2007), Comput Methods Programs Biomed, 86, 245 - 254
Predictors of capacity among inpatients: A UK perspective
Conference paper

Anthony DS. et al, (2007), SCHIZOPHRENIA BULLETIN, 33, 510 - 510
The inter-rater reliability of mental capacity assessments.
Journal article

Raymont V. et al, (2007), Int J Law Psychiatry, 30, 112 - 117
Cognitive neural plasticity during learning and recovery from brain damage
Journal article

Raymont V. and Grafman J., (2006), REPROGRAMMING THE BRAIN, 157, 199 - 206
Cognitive neural plasticity during learning and recovery from brain damage.
Journal article

Raymont V. and Grafman J., (2006), Prog Brain Res, 157, 199 - 206
Mental capacity and valid consent
Journal article

Hotopf M. and Raymont V., (2005), Foundation Years, 1, 18 - 20
Mental capacity of inpatients - Reply
Journal article

Hotopf M. et al, (2005), LANCET, 365, 569 - 569
Mental capacity of inpatients.
Journal article

O'Keeffe ST., (2005), Lancet, 365, 568 - 569
Prevalence of mental incapacity in medical inpatients and associated risk factors: cross-sectional study.
Journal article

Raymont V. et al, (2004), Lancet, 364, 1421 - 1427
Mental capacity and valid consent
Journal article

Hotopf M. and Raymont V., (2004), Psychiatry, 3, 8 - 10
Mental incapacity and medical ethics [3]
Journal article

Hudson SA. and Raymont V., (2004), British Journal of Psychiatry, 184, 84 - 85
Mental incapacity and medical ethics.
Journal article

Hudson SA. and Raymont V., (2004), Br J Psychiatry, 184, 84 - 85
The Maudsley bipolar disorder project. Clinical characteristics of bipolar disorder I in a Catchment area treatment sample.
Journal article

Raymont V. et al, (2003), Eur Psychiatry, 18, 13 - 17
The Maudsley Bipolar Disorder Project: the effect of medication, family history, and duration of illness on IQ and memory in bipolar I disorder.
Journal article

Donaldson S. et al, (2003), J Clin Psychiatry, 64, 86 - 93
The Maudsley bipolar disorder project. A survey of psychotropic prescribing patterns in bipolar I disorder.
Journal article

Frangou S. et al, (2002), Bipolar Disord, 4, 378 - 385
'Not in perfect mind' - The complexity of clinical capacity assessment
Journal article

Raymont V., (2002), Psychiatric Bulletin, 26, 201 - 204
Suicide in schizophrenia - How can research influence training and clinical practice?
Journal article

Raymont V., (2001), Psychiatric Bulletin, 25, 46 - 50

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Vanessa Raymont

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