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Professor Peter Brown obtained his medical degree from Cambridge University and thereafter joined the Medical Research Council Human Movement and Balance Unit before moving to the Institute of Neurology, London, where he also worked as a neurologist at the affiliated National Hospital for Neurology and Neurosurgery, London.  He moved to the University of Oxford as Professor of Experimental Neurology in 2010, and in 2015 became director of the Medical Research Council Brain Network Dynamics Unit at the University of Oxford.

Peter Brown

Professor of Experimental Neurology

Neural circuit dysfunction in Parkinson's and tremor

Research Summary

Experimental evidence repeatedly shows that there is abnormally synchronised oscillatory activity in the brains of people with Parkinson's disease.   Whether or not this aberrant brain activity causes any of the familiar motor symptoms of Parkinson's disease, or is simply a byproduct of the disease process is not known.  However, evidence is mounting to suggest that excessive oscillatory activity in the brain does cause a slowing of movement.  Much of the experimental evidence has come from Professor Peter Brown's group. 

The group takes a multidisciplinary approach combining experimental approaches with sophisticated signals analysis and modelling. The group's goal is to define how activity in large populations of neurons is coordinated in healthy movement and how such coordination may go awry in diseases.  Accordingly the group's ultimate aim is to translate their discoveries to improve treatment in Parkinson's Disease and other illnesses where similar principles apply. The group works closely with research programmes at the Medical Research Council Brain Network Dynamics Unit at the University of Oxford.

Sources of Funding

Key publications

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