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I am a Research Fellow at the FMRIB Centre setting up a dedicated translational imaging group applied to neurosurgical problems, particularly temporal lobe epilepsy and brain tumours.
I studied Experimental Psychology at Oxford (1999-2002) before completing a D.Phil at the FMRIB Centre (2002-2005) under the supervision of Prof. Paul Matthews focused on Temporal Lobe Epilepsy. Following a post-doctoral position with Prof. Tipu Aziz’s Deep Brain Stimulation research group, I spent 3 years as imaging scientist at the GlaxoSmithKline Clinical Imaging Centre (now Imanova), assessing the sensitivity of multi-modal neuroimaging measures as early markers of efficacy for drugs targeting memory impairment among others. In 2009, I moved to the MNI to work in the NeuroImaging of Epilepsy laboratory before returning to the Oxford FMRIB Centre on a MRC Fellowship later that year.
Research Fellow, FMRIB Centre
Our translational research uses non-invasive brain imaging measures to understand how chronic disease, particularly drug-resistant epilepsy and tumours, affects how the brain represents and processes information relevant to memory and other cognitive functions.
Focused on understanding mechanisms driving brain plasticity and behaviour, our research ultimately aims to improve individual patient management by identifying specific brain patterns predictive of clinical outcome after brain surgery. Accordingly, our multidisciplinary research, based at the FMRIB Centre, is conducted in close collaboration with both the Oxford Epilepsy Surgery Programme and Oncology neurosurgical service as well as neuroscientists at the Oxford Centre for Human Brain Activity.
Sources of Funding
- Medical Research Council
- British Medical Association
- John Fell Fund
- Medical Research Fund
- HDH Wills 1965 Charitable Trust
Improved localisation for 2-hydroxyglutarate detection at 3T using long-TE semi-LASER.
Berrington A. et al, (2016), Tomography, 2, 94 - 105
Noninvasive Quantification of 2-Hydroxyglutarate in Human Gliomas with IDH1 and IDH2 Mutations.
Emir UE. et al, (2016), Cancer Res, 76, 43 - 49
Thalamo-Cortical Disruption Contributes to Short-Term Memory Deficits in Patients with Medial Temporal Lobe Damage.
Voets NL. et al, (2015), Cereb Cortex, 25, 4584 - 4595
In response: Naming and recognition after laser amygdalohippocampotomy: Is the hippocampus involved?
Drane DL. et al, (2015), Epilepsia, 56, 1318 - 1319
Better object recognition and naming outcome with MRI-guided stereotactic laser amygdalohippocampotomy for temporal lobe epilepsy
Drane DL. et al, (2015), Epilepsia, 56, 101 - 113