Research groups
Colleges
Websites
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Laboratory for Cognitive Brain Mapping; RIKEN Brain Science Institute, Japan
Visiting Scientist
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Tohoku University Brain Science Center, Japan
Visiting Professor
Mark J. Buckley
MA DPhil
Professor of Behavioural and Cognitive Neuroscience
- Fellow of The Queen's College
Research Summary
I head the Brain and Behaviour Research Group in which we conduct basic neuroscience research to determine how neural systems underlie behaviour and cognition. Applied research aimed at relieving debilitating brain disease and disorders (e.g. dementias, amnesias, Schizophrenia, mood disorders etc.) depends crucially on basic research advancing understanding of how normal neural activity underlies normal behaviour, in addition to understanding why abnormal and dysfunctional behaviour may occur when these brain networks are compromised. For example, we have long been interested in understanding how brain areas in the temporal lobes and in associated regions, some of which become dysfunction in dementias including Alzheimer’s Disease, operate in mediating perception and memory. Likewise we have also focused our attention on understanding how more anterior brain regions in the frontal lobes operate in mediating learning and memory as well as other key elements of cognition including choice behaviour and goal-directed behaviour. An overarching theme of the current research in my laboratory is to progress beyond the traditional focus of research on individual regions and move to an understanding of how networks of interconnected brain regions interact together to mediate normal learning, memory and cognition. To do this we have to investigate both normal and abnormal brain function using a range of complementary neuropsychological, neurophysiological, and neuroimaging techniques. Our work is funded by the MRC, BBSRC, and Wellcome Trust.
Key publications
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Journal article
Mansouri FA. et al, (2017), Nat Rev Neurosci, 18, 645 - 657
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Journal article
Mansouri FA. et al, (2009), Nat Rev Neurosci, 10, 141 - 152
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Journal article
Buckley MJ. et al, (2009), Science, 325, 52 - 58
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Journal article
Mansouri FA. et al, (2007), Science, 318, 987 - 990
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Journal article
Rudebeck PH. et al, (2006), Science, 313, 1310 - 1312
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Journal article
Boschin EA. et al, (2015), Proc Natl Acad Sci U S A, 112, E1020 - E1027
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Journal article
Mansouri FA. et al, (2015), Proc Natl Acad Sci U S A, 112, E3940 - E3949
Recent publications
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Journal article
Maggi S. et al, (2024), Elife, 13
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Journal article
Mansouri F. et al, (2024), Nature Communications
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Journal article
Kadohisa M. et al, (2022), Neuron
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Journal article
Wu Z. et al, (2021), Eur J Neurosci
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A one-shot shift from explore to exploit in monkey prefrontal cortex
Journal article
Achterberg J. et al, (2021), The Journal of Neuroscience
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Journal article
Sallet J. et al, (2020), PLoS Biol, 18
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Journal article
Kadohisa M. et al, (2019), Cereb Cortex
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Journal article
Bridge H. et al, (2019), Elife, 8
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Chapter
Mansouri FA. and BUCKLEY MJ., (2018), Systems Neuroscience., 21
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Journal article
Browncross H. et al, (2018), Neuropsychologia
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Journal article
Ainsworth M. et al, (2018), Neuropsychologia, 119, 382 - 391
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Journal article
Ainsworth M. et al, (2018), Neuropsychologia, 119, 382 - 391
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Journal article
Browncross H. et al, (2018), Neuropsychologia
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Journal article
Isbister JB. et al, (2018), Interface Focus, 8
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Journal article
Papageorgiou GK. et al, (2017), Nat Commun, 8
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Journal article
Mansouri FA. et al, (2017), Nat Rev Neurosci, 18, 645 - 657
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Journal article
Boschin EA. et al, (2017), Neuropsychologia, 94, 36 - 43
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Journal article
Boschin EA. et al, (2017), Cereb Cortex, 27, 34 - 45
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Chapter
Tanaka K. et al, (2017), The Prefrontal Cortex as an Executive, Emotional, and Social Brain, 17 - 38
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Journal article
Mansouri FA. et al, (2017), Trends Neurosci, 40, 15 - 27