Contact information
Research groups
Websites
-
Translational Neuroimaging Group (TNG)
Research Group
-
FMRIB
NDCN Division
Ludovica Griffanti
Postdoctoral Researcher
PhD
I am a postdoctoral researcher at the Wellcome Centre for Integrative Neuroimaging (WIN), FMRIB. My current research focuses on brain MRI analysis in ageing, dementia and neurodegeneration with the aim to detect possible biomarkers especially for the pre-symptomatic phase of the disease.
I am currently involved in the collection, organisation and analysis of the Oxford Parkinson’s Disease Centre (OPDC) Discovery Cohort MRI sub-study. The OPDC aims to identify early changes in Parkinson’s disease patients before physical symptoms become apparent. The detection of the pre-symptomatic phase using biomarkers, including imaging markers, will allow for early diagnosis of the disease and early intervention through the use of potential neuroprotective therapies.
I am a member of the Translational Neuroimaging Group (TNG) and I am passionate about making research translational and applicable in clinical settings. To this aim I am currently involved in projects that aim to harmonise MRI-derived measures across sites/studies.
As a member of the WIN Analysis group I am also involved in the development of methodological approaches for structural MRI (automated lesions segmentation) and resting state fMRI (artefact removal and reproducibility assessments) part of FSL image analysis software package.
I am involved in post-graduate supervision and in teaching, both within the University of Oxford and at the international FSL course.
Key publications
-
BIANCA (Brain Intensity AbNormality Classification Algorithm): A new tool for automated segmentation of white matter hyperintensities.
Journal article
Griffanti L. et al, (2016), Neuroimage, 141, 191 - 205
-
Hand classification of fMRI ICA noise components.
Journal article
Griffanti L. et al, (2017), Neuroimage, 154, 188 - 205
Recent publications
-
SARS-CoV-2 is associated with changes in brain structure in UK Biobank.
Journal article
Douaud G. et al, (2022), Nature
-
Author Correction: Mapping brain structural differences and neuroreceptor correlates in Parkinson's disease visual hallucinations.
Journal article
Vignando M. et al, (2022), Nat Commun, 13
-
Mapping brain structural differences and neuroreceptor correlates in Parkinson's disease visual hallucinations.
Journal article
Vignando M. et al, (2022), Nat Commun, 13
-
Intrinsic network activity reflects the ongoing experience of chronic pain.
Journal article
Jahn P. et al, (2021), Sci Rep, 11
-
Association of cerebral small vessel disease burden with brain structure and cognitive and vascular risk trajectories in mid-to-late life.
Journal article
Jansen MG. et al, (2021), J Cereb Blood Flow Metab