Post-Doctoral Research Assistant
My research focuses on plasticity in the ageing brain, studying the effects of exercise and physical activity levels on brain structure and function. I am currently assessing the effects of a 12-week aerobic exercise intervention in the older population, combining multimodal MRI imaging with cognitive and physical assessment. I aim to analyse the potential benefits of exercise on memory and cognition in the elderly, and to further understand the underlying physiological mechanisms.
Increased burst-firing of ventral tegmental area dopaminergic neurons in D-amino acid oxidase knockout mice in vivo.
Schweimer JV. et al, (2014), Eur J Neurosci, 40, 2999 - 3009
D-amino acid oxidase is expressed in the ventral tegmental area and modulates cortical dopamine.
Betts JF. et al, (2014), Front Synaptic Neurosci, 6
Genetic mouse models relevant to schizophrenia: taking stock and looking forward.
Harrison PJ. et al, (2012), Neuropharmacology, 62, 1164 - 1167
LOCAL APPLICATION OF A D-AMINO ACID OXIDASE (DAO) INHIBITOR IN THE VENTRAL TEGMENTAL AREA INCREASES EXTRACELLULAR DOPAMINE IN THE RAT PREFRONTAL CORTEX IN VIVO
Betts JF. et al, (2011), JOURNAL OF PSYCHOPHARMACOLOGY, 25, A25 - A25
Co-Administration of the D-Amino Acid Oxidase Inhibitor, Sodium Benzoate, and D-Serine Increases Firing of Identified Dopamine Neurons in the Rat Ventral Tegmental Area in vivo
Schweimer JV. et al, (2011), BIOLOGICAL PSYCHIATRY, 69, 192S - 192S