Ivan Koychev
PhD MRCPsych
Senior Clinical Researcher
- Clinician Scientist Dementias Platform UK
- Consultant Neuropsychiatrist Oxford University Hospitals NHS Foundation Trust
I am a clinical academic psychiatrist (on the GMC Specialist Register for Old Age and General Adult Psychiatry) with a focus on the development of treatments for neuropsychiatric disorders. My research spans the key components of neuroscience clinical trial methodology: conduct of proof-of-concept (PoC) biomarker-based clinical trials in surrogate populations, testing of repurposed compounds, development of stratification and efficacy biomarkers and creation of infrastructure for large-scale stratified recruitment into neuroscience experimental medicine studies and clinical trials. Clinically, I focus on the assessment and management of patients with neuropsychiatric presentations in acute medical settings.
Recent publications
-
Associations between sex and lifestyle activities with cognitive reserve in mid-life adults with genetic risk for Alzheimer's disease.
Journal article
Qi Q. et al, (2024), Alzheimers Res Ther, 16
-
Neurodegenerative fluid biomarkers are enriched in human cervical lymph nodes.
Journal article
Al-Diwani A. et al, (2024), Brain
-
Safety, tolerability, and efficacy outcomes of the Investigation of Levetiracetam in Alzheimer's disease (ILiAD) study: a pilot, double-blind placebo-controlled crossover trial.
Journal article
Sen A. et al, (2024), Epilepsia Open
-
12-month neurological and psychiatric outcomes of semaglutide use for type 2 diabetes: a propensity-score matched cohort study
Journal article
De Giorgi R. et al, (2024), eClinicalMedicine, 74
-
Neuroimaging and Clinical Findings in Healthy Middle-Aged Adults With Mild Traumatic Brain Injury in the PREVENT Dementia Study.
Journal article
Low A. et al, (2024), JAMA Netw Open, 7