Ivan Koychev
PhD MRCPsych
Senior Clinical Researcher
- Clinician Scientist Dementias Platform UK
- Consultant Neuropsychiatrist Oxford University Hospitals NHS Foundation Trust
I am a clinical academic psychiatrist (on the GMC Specialist Register for Old Age and General Adult Psychiatry) with a focus on the development of treatments for neuropsychiatric disorders. My research spans the key components of neuroscience clinical trial methodology: conduct of proof-of-concept (PoC) biomarker-based clinical trials in surrogate populations, testing of repurposed compounds, development of stratification and efficacy biomarkers and creation of infrastructure for large-scale stratified recruitment into neuroscience experimental medicine studies and clinical trials. Clinically, I focus on the assessment and management of patients with neuropsychiatric presentations in acute medical settings.
Recent publications
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Neurodegenerative disease of the brain: a survey of interdisciplinary approaches
Journal article
Davenport F. et al, (2023), Journal of the Royal Society, Interface, 20
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Modifiable and non-modifiable risk factors of dementia on midlife cerebral small vessel disease in cognitively healthy middle-aged adults: the PREVENT-Dementia study.
Journal article
Low A. et al, (2022), Alzheimers Res Ther, 14
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Macrostructural brain alterations at midlife are connected to cardiovascular and not inherited risk of future dementia: the PREVENT-Dementia study.
Journal article
Dounavi M-E. et al, (2022), J Neurol, 269, 4299 - 4309
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Personalised treatment for cognitive impairment in dementia: development and validation of an artificial intelligence model.
Journal article
Liu Q. et al, (2022), BMC Med, 20
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Modifiable risk factors for dementia, and awareness of brain health behaviors: Results from the Five Lives Brain Health Ireland Survey (FLBHIS).
Journal article
Dukelow T. et al, (2022), Front Psychol, 13