Andreas Themistocleous
BSc(Hons), MBBCh, PhD, FCP (SA), MRCP (UK)
Clinical Research Fellow
Research Summary
My research is focused on understanding the mechanisms of neuropathic pain. I use a combination of techniques, such as threshold tracking, intraepidermal nerve fibre density assessment and quantitative sensory testing, to assess the functional and structural integrity of the peripheral nervous system. These techniques allow me to explore peripheral neuronal processing in patients suffering from peripheral neuropathy. Most of my current research is focused on characterising the somatosensory, histological and electrophysiological phenotype of patients with diabetic neuropathic pain.
Recent publications
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Investigating genotype-phenotype relationship of extreme neuropathic pain disorders in a national cohort: ’NIHR Bioresources Rare Disease – Neuropathic Pain Disorders’
Journal article
BENNETT D. and THEMISTOCLEOUS A., (2022), Brain Communications
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Classification of painful or painless diabetic peripheral neuropathy and identification of the most powerful predictors using machine learning models in large cross-sectional cohorts.
Journal article
Baskozos G. et al, (2022), BMC Med Inform Decis Mak, 22
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Malleability of the cortical hand map following a finger nerve block.
Journal article
Wesselink DB. et al, (2022), Sci Adv, 8
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Axonal excitability does not differ between painful and painless diabetic or chemotherapy-induced distal symmetrical polyneuropathy in a multi-centre observational study.
Journal article
Themistocleous AC. et al, (2022), Ann Neurol
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Nav1.7 is required for normal C-low threshold mechanoreceptor function in humans and mice.
Journal article
Middleton SJ. et al, (2021), Brain