Andreas Themistocleous
BSc(Hons), MBBCh, PhD, FCP (SA), MRCP (UK)
Clinical Research Fellow
Research Summary
My research is focused on understanding the mechanisms of neuropathic pain. I use a combination of techniques, such as threshold tracking, intraepidermal nerve fibre density assessment and quantitative sensory testing, to assess the functional and structural integrity of the peripheral nervous system. These techniques allow me to explore peripheral neuronal processing in patients suffering from peripheral neuropathy. Most of my current research is focused on characterising the somatosensory, histological and electrophysiological phenotype of patients with diabetic neuropathic pain.
Recent publications
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Classification of painful or painless diabetic peripheral neuropathy and identification of the most powerful predictors using machine learning models in large cross-sectional cohorts.
Journal article
Baskozos G. et al, (2022), BMC Med Inform Decis Mak, 22
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Safety and immunogenicity of ChAdOx1 nCoV-19 vaccine administered in a prime-boost regimen in young and old adults (COV002): a single-blind, randomised, controlled, phase 2/3 trial.
Journal article
Ramasamy MN. et al, (2021), Lancet, 396, 1979 - 1993
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LGI1- versus CASPR2-antibody neuropathic pain: clinical and biological comparisons.
Journal article
Ramanathan S. et al, (2021), Ann Neurol
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Painful and non-painful diabetic neuropathy, diagnostic challenges and implications for future management.
Journal article
Jensen TS. et al, (2021), Brain, 144, 1632 - 1645
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Studying human nociceptors: from fundamentals to clinic.
Journal article
Middleton SJ. et al, (2021), Brain, 144, 1312 - 1335