Andreas Themistocleous
BSc(Hons), MBBCh, PhD, FCP (SA), MRCP (UK)
Clinical Research Fellow
Research Summary
My research is focused on understanding the mechanisms of neuropathic pain. I use a combination of techniques, such as threshold tracking, intraepidermal nerve fibre density assessment and quantitative sensory testing, to assess the functional and structural integrity of the peripheral nervous system. These techniques allow me to explore peripheral neuronal processing in patients suffering from peripheral neuropathy. Most of my current research is focused on characterising the somatosensory, histological and electrophysiological phenotype of patients with diabetic neuropathic pain.
Recent publications
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Safety and immunogenicity of ChAdOx1 nCoV-19 vaccine administered in a prime-boost regimen in young and old adults (COV002): a single-blind, randomised, controlled, phase 2/3 trial.
Journal article
Ramasamy MN. et al, (2021), Lancet, 396, 1979 - 1993
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Axonal swellings are related to type 2 diabetes, but not to distal diabetic sensorimotor polyneuropathy.
Journal article
Karlsson P. et al, (2021), Diabetologia, 64, 923 - 931
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T cell and antibody responses induced by a single dose of ChAdOx1 nCoV-19 (AZD1222) vaccine in a phase 1/2 clinical trial.
Journal article
Ewer KJ. et al, (2021), Nat Med, 27, 270 - 278
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Phase 1/2 trial of SARS-CoV-2 vaccine ChAdOx1 nCoV-19 with a booster dose induces multifunctional antibody responses.
Journal article
Barrett JR. et al, (2020), Nat Med
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Safety and efficacy of the ChAdOx1 nCoV-19 vaccine (AZD1222) against SARS-CoV-2: an interim analysis of four randomised controlled trials in Brazil, South Africa, and the UK.
Journal article
Voysey M. et al, (2020), Lancet