Importance of the COMT gene for sex differences in brain function and predisposition to psychiatric disorders.
Journal article
Tunbridge EM. and Harrison PJ., (2011), Curr Top Behav Neurosci, 8, 119 - 140
A B2 SINE insertion in the Comt1 gene (Comt1(B2i)) results in an overexpressing, behavior modifying allele present in classical inbred mouse strains.
Journal article
Kember RL. et al, (2010), Genes Brain Behav, 9, 925 - 932
Human brain weight is correlated with expression of the 'housekeeping genes' beta-2-microglobulin (β2M) and TATA-binding protein (TBP).
Journal article
Harrison PJ. et al, (2010), Neuropathol Appl Neurobiol, 36, 498 - 504
INVESTIGATION OF THE ROLE OF CATECHOL-O-METHYLTRANSFERASE(COMT) ON HIPPOCAMPUS-DEPENDENT BEHAVIOUR
Conference paper
Laatikainen LM. et al, (2010), JOURNAL OF PSYCHOPHARMACOLOGY, 24, A67 - A67
SEXUALLY DIMORPHIC EFFECTS OF COMT ON COGNITION AND IN PSYCHIATRIC DISORDERS
Conference paper
Tunbridge EM., (2010), JOURNAL OF PSYCHOPHARMACOLOGY, 24, A5 - A5
Epistatic and functional interactions of catechol-o-methyltransferase (COMT) and AKT1 on neuregulin1-ErbB signaling in cell models.
Journal article
Sei Y. et al, (2010), PLoS One, 5
The Role of Catechol-O-Methyltransferase (COMT) in Modulating Hippocampal Dopaminergic Metabolism and Behaviour
Conference paper
Laatikainen LM. et al, (2010), BIOLOGICAL PSYCHIATRY, 67, 214S - 215S
The catechol-O-methyltransferase gene: its regulation and polymorphisms.
Journal article
Tunbridge EM., (2010), Int Rev Neurobiol, 95, 7 - 27
COMT AND HIPPOCAMPAL FUNCTION: THE COMT INHIBITOR TOLCAPONE MODULATES FIELD EXCITATORY POSTSYNAPTIC POTENTIALS IN CA1 SCHAFFER COLLATERAL AND PERFORANT PATHWAYS
Conference paper
Tunbridge E. et al, (2009), SCHIZOPHRENIA BULLETIN, 35, 54 - 55
Catechol-O-methyltransferase (COMT): a gene contributing to sex differences in brain function, and to sexual dimorphism in the predisposition to psychiatric disorders.
Journal article
Harrison PJ. and Tunbridge EM., (2008), Neuropsychopharmacology, 33, 3037 - 3045
Polymorphisms in the catechol-O-methyltransferase (COMT) gene influence plasma total homocysteine levels.
Journal article
Tunbridge EM. et al, (2008), Am J Med Genet B Neuropsychiatr Genet, 147B, 996 - 999
Neuregulin1-induced cell migration is impaired in schizophrenia: association with neuregulin1 and catechol-o-methyltransferase gene polymorphisms.
Journal article
Sei Y. et al, (2007), Mol Psychiatry, 12, 946 - 957
Expression of multiple catechol-o-methyltransferase (COMT) mRNA variants in human brain.
Journal article
Tunbridge EM. et al, (2007), Am J Med Genet B Neuropsychiatr Genet, 144B, 834 - 839
Catechol-o-methyltransferase enzyme activity and protein expression in human prefrontal cortex across the postnatal lifespan.
Journal article
Tunbridge EM. et al, (2007), Cereb Cortex, 17, 1206 - 1212
Expression and functional impact of multiple catechol-o-methyltransferase (COMT) mRNA variants
Conference paper
Lane TA. et al, (2007), BIOLOGICAL PSYCHIATRY, 61, 174S - 174S
Human plasma homocysteine levels are associated with the catechol-O-methyltransferase Val158Met polymorphism
Conference paper
Tunbridge EM. et al, (2007), BIOLOGICAL PSYCHIATRY, 61, 191S - 191S
Detection and expression of multiple catechol-o-methyltransferase mRNA variants in human brain
Conference paper
Tunbridge E. et al, (2007), SCHIZOPHRENIA BULLETIN, 33, 267 - 267
Catechol-o-methyltransferase, cognition, and psychosis: Val158Met and beyond.
Journal article
Tunbridge EM. et al, (2006), Biol Psychiatry, 60, 141 - 151
COMT inhibition enhances neuregulin-induced cell migration in B lymphoblasts
Conference paper
Tunbridge EM. et al, (2006), BIOLOGICAL PSYCHIATRY, 59, 44S - 44S
A novel protein isoform of catechol O-methyltransferase (COMT): brain expression analysis in schizophrenia and bipolar disorder and effect of Val158Met genotype.
Journal article
Tunbridge EM. et al, (2006), Mol Psychiatry, 11, 116 - 117