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Publications

The functional characteristics of optogenetic gene therapy for vision restoration

HANKINS M. et al, (2020), Cellular and Molecular Life Sciences

The functional characteristics of optogenetic gene therapy for vision restoration

HANKINS M. et al, (2020), Cellular and Molecular Life Sciences

Differential roles for cryptochromes in the mammalian retinal clock.

Wong JCY. et al, (2018), FASEB J, 32, 4302 - 4314

Functional characterisation of naturally occurring mutations in human melanopsin.

Rodgers J. et al, (2018), Cell Mol Life Sci

Long-term restoration of visual function in end-stage retinal degeneration using subretinal human melanopsin gene therapy.

De Silva SR. et al, (2017), Proc Natl Acad Sci U S A, 114, 11211 - 11216

Expression and localisation of two-pore domain (K2P) background leak potassium ion channels in the mouse retina.

Hughes S. et al, (2017), Sci Rep, 7

Constant Light Desynchronizes Olfactory versus Object and Visuospatial Recognition Memory Performance.

Tam SKE. et al, (2017), J Neurosci, 37, 3555 - 3567

Modulation of recognition memory performance by light requires both melanopsin and classical photoreceptors.

Tam SKE. et al, (2016), Proc Biol Sci, 283

Attenuated pupillary light responses and downregulation of opsin expression parallel decline in circadian disruption in two different mouse models of Huntington's disease.

Ouk K. et al, (2016), Hum Mol Genet, 25

Inhibitory effects of fluoxetine on photosensitive retinal ganglion cells

Hughes S. et al, (2016), INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 57

Attenuated pupillary light responses and downregulation of opsin expression parallel decline in circadian disruption in two different mouse models of Huntington's disease.

Ouk K. et al, (2016), Hum Mol Genet

Characterisation of light responses in the retina of mice lacking principle components of rod, cone and melanopsin phototransduction signalling pathways.

Hughes S. et al, (2016), Sci Rep, 6

Melanopsin Regulates Both Sleep-Promoting and Arousal-Promoting Responses to Light.

Pilorz V. et al, (2016), PLoS Biol, 14

Signalling by melanopsin (OPN4) expressing photosensitive retinal ganglion cells.

Hughes S. et al, (2016), Eye (Lond), 30, 247 - 254

Circadian profiling in two mouse models of lysosomal storage disorders; Niemann Pick type-C and Sandhoff disease.

Richardson K. et al, (2016), Behav Brain Res, 297, 213 - 223

Human Opsin-G-Protein Fusion Proteins as Potential Light Sensitisers for Optogenetic Gene Therapy for Retinal Degeneration

Hickey D. et al, (2015), CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY, 43, 26 - 27

Isoforms of Melanopsin Mediate Different Behavioral Responses to Light.

Jagannath A. et al, (2015), Curr Biol, 25, 2430 - 2434

Characterisation of a novel ENU-induced spectral tuning mutation in melanopsin

Rodgers J. et al, (2015), INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 56

The hypothalamic photoreceptors regulating seasonal reproduction in birds: a prime role for VA opsin.

García-Fernández JM. et al, (2015), Front Neuroendocrinol, 37, 13 - 28

Photic regulation of clock systems

Hughes S. et al, (2015), Methods in Enzymology, 552, 125 - 143

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