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Publications

Xist-mediated silencing requires additive functions of SPEN and Polycomb together with differentiation-dependent recruitment of SmcHD1

Journal article

Bowness J. et al, (2022), Cell Reports

Prion-like domains drive CIZ1 assembly formation at the inactive X chromosome.

Journal article

Sofi S. et al, (2022), J Cell Biol, 221

Locus-specific expression of transposable elements in single cells with CELLO-seq.

Journal article

Berrens RV. et al, (2021), Nat Biotechnol

Acute depletion of METTL3 implicates N6-methyladenosine in alternative intron/exon inclusion in the nascent transcriptome

Journal article

BROCKDORFF N. et al, (2021), Genome Research

Progress toward understanding chromosome silencing by Xist RNA.

Journal article

Brockdorff N. et al, (2020), Genes Dev, 34, 733 - 744

The many faces of Polycomb regulation by RNA.

Journal article

Almeida M. et al, (2020), Curr Opin Genet Dev, 61, 53 - 61

The role of the Xist 5' m6A region and RBM15 in X chromosome inactivation.

Journal article

Coker H. et al, (2020), Wellcome Open Res, 5

Localized accumulation of Xist RNA in X chromosome inactivation.

Journal article

Brockdorff N., (2019), Open Biol, 9

m6A modification of non-coding RNA and the control of mammalian gene expression.

Journal article

Coker H. et al, (2019), Biochim Biophys Acta Gene Regul Mech, 1862, 310 - 318

Selective Roles of Vertebrate PCF11 in Premature and Full-Length Transcript Termination.

Journal article

Kamieniarz-Gdula K. et al, (2019), Mol Cell

The non-canonical SMC protein SmcHD1 antagonises TAD formation and compartmentalisation on the inactive X chromosome.

Journal article

Gdula MR. et al, (2019), Nat Commun, 10

Smchd1 Targeting to the Inactive X Is Dependent on the Xist-HnrnpK-PRC1 Pathway.

Journal article

Jansz N. et al, (2018), Cell Rep, 25, 1912 - 1923.e9

Local Tandem Repeat Expansion in Xist RNA as a Model for the Functionalisation of ncRNA.

Journal article

Brockdorff N., (2018), Noncoding RNA, 4

Unbiased Genetic Screen to Identify Factors Involved in X-Chromosome Inactivation Using a Pooled Bar-Coded shRNA Library.

Chapter

Moindrot B. and Brockdorff N., (2018), 1861, 19 - 36

hnRNPK Recruits PCGF3/5-PRC1 to the Xist RNA B-Repeat to Establish Polycomb-Mediated Chromosomal Silencing.

Journal article

Pintacuda G. et al, (2017), Mol Cell, 68, 955 - 969.e10

Polycomb complexes in X chromosome inactivation.

Journal article

Brockdorff N., (2017), Philos Trans R Soc Lond B Biol Sci, 372

Preface

Journal article

Heard E. and Brockdorff N., (2017), Philosophical Transactions of the Royal Society B: Biological Sciences, 372

Preface.

Book

Heard E. and Brockdorff N., (2017), 372

Polycomb complexes in X chromosome inactivation

Conference paper

Brockdorff N., (2017), Philosophical Transactions of the Royal Society B: Biological Sciences

PCGF3/5-PRC1 initiates Polycomb recruitment in X chromosome inactivation.

Journal article

Almeida M. et al, (2017), Science, 356, 1081 - 1084

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