Degradation of a cohesin subunit by the N-end rule pathway is essential for chromosome stability
Candido EPM., Rao H., Uhlmann F., Nasmyth K., Varshavsky A.
This article demonstrates that the N-end rule pathway of ubiquitin-dependent proteolysis is required for degradation of a subunit of cohesin, a protein which functions to keep sister chromatids together at metaphase.