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We studied 957 cases of primary (idiopathic) dystonia and found a significant excess of female patients for segmental and focal dystonia. A novel observation was a significantly earlier age at onset in males as opposed to females for primary segmental (mean age, 44.6 versus 53.3) and focal dystonia (43.8 versus 47.8). This trend was also apparent in cervical dystonia, blepharospasm, and laryngeal dystonia. For writer's cramp and focal limb dystonia, this trend was reversed with an earlier age at onset in females. These results suggest that focal dystonia should not be treated as an homogenous group, and sex-linked factors may play a role.

Original publication

DOI

10.1212/wnl.53.8.1871

Type

Journal article

Journal

Neurology

Publication Date

10/11/1999

Volume

53

Pages

1871 - 1873

Keywords

Adult, Age Distribution, Age of Onset, Dystonia, Europe, Female, Humans, Male, Middle Aged, Sex Distribution