How, when, and why do lymphocytes die?
Strasser A., Newton K., O'Reilly LA., Pellegrini M., O'Connor L., Puthalakath H., Culien L., Tai L., Coultas L., Huang DCS., Villunger A., Bouillet P., Bath ML., Vaux DL., Cory S., Adams JM., Harris AW.
Apoptosis represents a critical process in the immune system, in tissue modeling, in cell homeostasis, and in defense against pathogens. Here, Andreas Strasser and colleagues detail the comprehensive studies carried out at the Hall Institute into this phenomenon, and highlight the identification of molecular control mechanisms of apoptosis pathways that they have made.