Cookies on this website
We use cookies to ensure that we give you the best experience on our website. If you click 'Continue' we'll assume that you are happy to receive all cookies and you won't see this message again. Click 'Find out more' for information on how to change your cookie settings.

In summary, hyperekplexia is characterised by an abnormal startle response that is relayed in the brainstem and likely involves a pathological exaggeration of the physiological startle reflex. The physiological and pathological startle responses are mutable, being modulated by a number of factors, including posture and gait. The hyperekplectic startle is but one of several abnormal features in hyperekplexia, reflecting the distributed nature of glycinergic receptors within the central nervous system.


Journal article


Movement Disorders

Publication Date