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Three-dimensional images of the open state of the nicotinic acetylcholine receptor have been obtained at 9 A resolution. Comparison with the closed state reveals the structural basis of channel gating.

Type

Journal article

Journal

Curr Biol

Publication Date

01/04/1995

Volume

5

Pages

373 - 375

Keywords

Acetylcholine, Amino Acid Sequence, Ion Channel Gating, Molecular Sequence Data, Protein Conformation, Receptors, Nicotinic