Cookies on this website

We use cookies to ensure that we give you the best experience on our website. If you click 'Accept all cookies' we'll assume that you are happy to receive all cookies and you won't see this message again. If you click 'Reject all non-essential cookies' only necessary cookies providing core functionality such as security, network management, and accessibility will be enabled. Click 'Find out more' for information on how to change your cookie settings.

Genomic and cDNA clones of an Msx class homeobox gene were isolated from amphioxus (Branchiostoma floridae). The gene, AmphiMsx, is expressed in the neural plate from late gastrulation; in later embryos it is expressed in dorsal cells of the neural tube, excluding anterior and posterior regions, in an irregular reiterated pattern. There is transient expression in dorsal cells within somites, reminiscent of migrating neural crest cells of vertebrates. In larvae, mRNA is detected in two patches of anterior ectoderm proposed to be placodes. Evolutionary analyses show there is little phylogenetic information in Msx protein sequences; however, it is likely that duplication of Msx genes occurred in the vertebrate lineage.


Journal article


Dev Genes Evol

Publication Date





260 - 263


Amino Acid Sequence, Animals, Chordata, Nonvertebrate, DNA, Complementary, Embryo, Nonmammalian, Gene Expression Regulation, Developmental, Genes, Homeobox, In Situ Hybridization, Larva, Molecular Sequence Data, Nerve Tissue Proteins, Nervous System, Sequence Alignment, Sequence Analysis, DNA, Sequence Homology, Amino Acid