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Activation and inactivation of Rab GTPases by GEFs and GAPs promotes or terminates vesicle tethering to organelles, respectively. This simple model is challenged by new evidence revealing that a catalytically inactive Rab GAP promotes rather than terminates vesicle tethering at the trans-Golgi.

Original publication

DOI

10.1016/j.cub.2017.10.003

Type

Journal article

Journal

Curr Biol

Publication Date

20/11/2017

Volume

27

Pages

R1222 - R1225