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The changes in cyanide-resistant and SHAM-sensitive respiration have been examined in the cell cycle of yeast cells synchronized by nutrient starvation. The changing of the cyanide-resistant respiration of cells proliferating in synchronizing fermentor, where the glucose concentration was continuously decreasing, was associated with the stage in cell cycle rather than with the alteration of environment. The cyanide-resistant alternative respiration may be attributed characteristic of a certain part of the cell cycle termed "A" phase. This hypothesis is supported by the observation that in cultures proliferating, synchronously under constant conditions, the cyanide-resistant respiration changes periodically and reaches its maximum in the "A" phase after the cell division.


Journal article


Acta Microbiol Hung

Publication Date





269 - 276


Candida/drug effects/*physiology Cell Cycle Microbiological Techniques Oxygen Consumption/drug effects Potassium Cyanide/pharmacology Salicylamides/pharmacology