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The authors examined variations of serotonin transporter-linked promoter region (5-HTTLPR) functional polymorphism in 26 stroke patients with major depression and in 25 unrelated nondepressed stroke subjects of Caucasian descent. Findings indicate a significant association between 5-HTTLPR short variant genotype and poststroke major depression.

Original publication

DOI

10.1176/jnp.18.1.96

Type

Journal article

Journal

J Neuropsychiatry Clin Neurosci

Publication Date

2006

Volume

18

Pages

96 - 99

Keywords

Adult, Aged, Aged, 80 and over, Alleles, Depressive Disorder, Major, Female, Genetic Predisposition to Disease, Genotype, Humans, Male, Middle Aged, Polymorphism, Genetic, Promoter Regions, Genetic, Serotonin Plasma Membrane Transport Proteins, Statistics as Topic, Stroke