Cookies on this website
We use cookies to ensure that we give you the best experience on our website. If you click 'Continue' we'll assume that you are happy to receive all cookies and you won't see this message again. Click 'Find out more' for information on how to change your cookie settings.

BACKGROUND AND PURPOSE: Only a small percentage of stroke patients are treated with thrombolytic therapy. We sought to determine whether vessel occlusion in mild strokes represented a new target population for interventional therapy. METHODS: We imaged 106 acute stroke patients with MRI. Patients were identified with evidence of middle cerebral artery (MCA) occlusion and mild or no stroke signs (National Institutes of Health Stroke Scale [NIHSS] <or=3). They were compared with patients with signs of stroke, NIHSS >3, and MCA occlusion. RESULTS: We identified 5 patients with absent flow on MRA in the MCA and mild or no stroke signs (NIHSS <or=3). All 5 were functionally independent at 3 months. CONCLUSIONS: Caution should be exercised in considering thrombolytic therapy in these patients. Quantification of perfusion imaging is required to identify "at risk" mild stroke populations.

Original publication

DOI

10.1161/01.STR.0000110985.01773.7F

Type

Journal article

Journal

Stroke

Publication Date

02/2004

Volume

35

Pages

469 - 471

Keywords

Acute Disease, Aged, Blood Flow Velocity, Cerebrovascular Circulation, Diffusion Magnetic Resonance Imaging, Female, Humans, Infarction, Middle Cerebral Artery, Ischemic Attack, Transient, Magnetic Resonance Angiography, Male, Middle Aged, Middle Cerebral Artery, Predictive Value of Tests, Prospective Studies, Recovery of Function, Severity of Illness Index, Stroke, Tomography, X-Ray Computed