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The authors measured the association of early ischemic change on CT scan, measured using the Alberta Stroke Programme Early CT score (ASPECTS), and functional outcome in 825 patients with anterior circulation stroke treated with IV thrombolysis within 3 hours of onset. ASPECTS predicted outcome in a graded fashion (linearly for ASPECTS 6 through 10; pattern ill-defined for ASPECTS 0 through 5) but discriminated individual outcomes weakly. Except perhaps when early ischemic change is extensive, clinicians should not estimate prognosis using ASPECTS alone.

Original publication

DOI

10.1212/01.wnl.0000228221.44334.73

Type

Journal article

Journal

Neurology

Publication Date

08/08/2006

Volume

67

Pages

516 - 518

Keywords

Acute Disease, Aged, Aged, 80 and over, Female, Humans, Male, Middle Aged, Predictive Value of Tests, Stroke, Tissue Plasminogen Activator