Target highlights from the first post-PSI CASP experiment (CASP12, May-August 2016).
Kryshtafovych A., Albrecht R., Baslé A., Bule P., Caputo AT., Carvalho AL., Chao KL., Diskin R., Fidelis K., Fontes CMGA., Fredslund F., Gilbert HJ., Goulding CW., Hartmann MD., Hayes CS., Herzberg O., Hill JC., Joachimiak A., Kohring G-W., Koning RI., Lo Leggio L., Mangiagalli M., Michalska K., Moult J., Najmudin S., Nardini M., Nardone V., Ndeh D., Nguyen T-H., Pintacuda G., Postel S., van Raaij MJ., Roversi P., Shimon A., Singh AK., Sundberg EJ., Tars K., Zitzmann N., Schwede T.
The functional and biological significance of the selected CASP12 targets are described by the authors of the structures. The crystallographers discuss the most interesting structural features of the target proteins and assess whether these features were correctly reproduced in the predictions submitted to the CASP12 experiment.