Cookies on this website

We use cookies to ensure that we give you the best experience on our website. If you click 'Accept all cookies' we'll assume that you are happy to receive all cookies and you won't see this message again. If you click 'Reject all non-essential cookies' only necessary cookies providing core functionality such as security, network management, and accessibility will be enabled. Click 'Find out more' for information on how to change your cookie settings.

Working memory is implicated in various higher-order cognitive operations. We hypothesized that the availability of a temporal representation in working memory would limit the extent of cortico-cortical coupling necessary to undertake a self-paced rhythmic movement. To this end we examined modulations in cortico-cortical interactions as determined by EEG coherence during a delay interval and subsequent movement reproduction. Right hand movement was initially paced by a metronome beat every 0.9 s, followed by a delay interval, after which hand movement was repeated in an unpaced manner. Movement reproduction after a long (22.5 s, corresponding to 25 movement cycles) compared to a short (5.4 s, corresponding to 6 movement cycles) delay interval was associated with an increased degree of functional coupling in the beta frequency band (12-30 Hz) of the left (movement-driving) hemisphere (F3-FC3, F3-C3 and F3-P3 connections) as well as mesial regions (FCz-FC3, FCz-C3 and Cz-FC3 connections) even though overall behavioral characteristics were not influenced. In addition, analysis of the EEG coherence in the delay period revealed a bilateral frontal network (F3-F4, F3-FC4, F4-FC3 and FC3-FC4 connections). Activity in the latter tended to be synchronized in the theta band (4-8 Hz) and was significantly less strong at 22.5 s than 5.4 s. These data suggest that working memory may be partly subserved by synchronization in a bilateral frontal network and may provide an intrinsic contextual influence that shapes the pattern of cortico-cortical interaction during a given task.

Original publication




Journal article


Exp Brain Res

Publication Date





204 - 210


Biomechanical Phenomena, Electrodes, Electroencephalography, Functional Laterality, Humans, Memory, Short-Term, Motor Cortex, Movement, Nerve Net, Psychomotor Performance, Theta Rhythm