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Centrosome amplification is a common feature of many types of cancer, but whether it is a cause or consequence is hotly debated. In this issue of Developmental Cell, Levine et al. (2017) provide strong evidence that centrosome amplification is sufficient to initiate tumorigenesis in a mouse model.

Original publication

DOI

10.1016/j.devcel.2017.01.009

Type

Journal article

Journal

Dev Cell

Publication Date

06/02/2017

Volume

40

Pages

217 - 218

Keywords

Animals, Cell Transformation, Neoplastic, Centrosome, Neoplasms