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A major goal in organ transplantation has been to safely exploit the natural processes of immune tolerance in order to minimize the dose and duration of drug immunosuppression. In this commentary, I argue that we can learn from how tumours avoid rejection, to evolve a three-stage tolerance-inducing strategy for transplanted tissues.

Original publication

DOI

10.1111/cei.12933

Type

Journal article

Journal

Clin Exp Immunol

Publication Date

08/2017

Volume

189

Pages

135 - 137

Keywords

anergy, suppression, tolerance, transplantation, tumour immunology, Graft Rejection, Humans, Immune Evasion, Immunosuppression, Neoplasms, Organ Transplantation, Transplantation Immunology, Transplantation Tolerance