Diverse origins of conformational equilibrium isotope effects for hydrogen in 1,3-dioxans
Carr CA., Ellison SLR., Robinson MJT.
Conformational equilibrium isotope effects in derivatives of 1,3-dioxan are consistent with four distinct origins: (i) steric hindrance, (ii) the anomeric effect, (iii) orbital interactions between C-H bonds and either non-bonding electrons through three or more coplanar bonds or (C-O)σ*orbitals, and (iv) a difference in polarity between C-H and C-D. © 1989.