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The multiple roles of the Drosophila epidermal growth factor receptor (EGFR) require that its activation is regulated precisely. Recent work has highlighted two important control mechanisms: the existence of multiple ligands with distinct properties and the interaction between EGFR pathway and other signalling pathways. The integration of signalling pathways into networks is beginning to be understood.


Journal article


Curr Opin Genet Dev

Publication Date





407 - 411


Animals, Drosophila, Drosophila Proteins, Eye Proteins, Ligands, Nerve Tissue Proteins, Receptor, Epidermal Growth Factor, Signal Transduction