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© 2015 International Parkinson and Movement Disorder Society. The subthalamic nucleus (STN), which is currently the most common target for deep brain stimulation (DBS) for Parkinson's disease (PD), has received increased attention over the past few years for the roles it may play in functions beyond simple motor control. In this article, we highlight several of the theoretical, interventional, and electrophysiological studies that have implicated the STN in response inhibition. Most influential among this evidence has been the reported effect of STN DBS in increasing impulsive responses in the laboratory setting. Yet, how this relates to pathological impulsivity in patients' everyday lives remains uncertain.

Original publication

DOI

10.1002/mds.26072

Type

Journal article

Journal

Movement Disorders

Publication Date

01/03/2015

Volume

30

Pages

328 - 338