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In this issue, Sorbara et al. (2014) demonstrate that axonal transport impairment is an early feature of neurodegeneration in multiple sclerosis models. This transport deficit is reversible by anti-inflammatory intervention but, if untreated, can contribute to late-stage axonal dystrophy.

Original publication

DOI

10.1016/j.neuron.2014.12.012

Type

Journal article

Journal

Neuron

Publication Date

17/12/2014

Volume

84

Pages

1105 - 1107

Keywords

Animals, Axonal Transport, Axons, Multiple Sclerosis