Comparison of the α-globin gene cluster structure in Perissodactyla
Flint J., Ryder OA., Clegg JB.
To investigate molecular evolution in a mammalian order with a comprehensive fossil record, we have constructed α-globin-like gene cluster maps for members of the order Perissodactyla. Although the arrangement of genes is the same in the five Equidae examined, the tapir and rhinoceros differ from each other and the horse in the position and number of their ζ genes, but not in the arrangement of their α and θ genes. In contrast to morphological work, a dendrogram derived from restriction site maps associates the tapir with the horse rather than with the rhinoceros; however, this phylogeny is not statistically significant. Among the Equidae, Equus caballus emerges as an outgroup, in agreement with data from other disciplines. © 1990 Springer-Verlag New York Inc.