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Recently, Canadian, US and European health regulatory agencies issued warnings about an increased risk of stroke and death in elderly patients with dementia receiving atypical antipsychotics. Assessing both randomised and non-randomised evidence, this systematic review found conflicting findings, particularly for risperidone. More research is needed to better inform clinical practice.

Type

Journal article

Journal

Mini Rev Med Chem

Publication Date

07/2008

Volume

8

Pages

776 - 783

Keywords

Aged, Antipsychotic Agents, Cerebrovascular Disorders, Dementia, Humans