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MicroRNAs (miRNAs) are versatile regulators of gene expression in higher eukaryotes. In order to silence many different mRNAs in a precise manner, miRNA stability and efficacy is controlled by highly developed regulatory pathways and fine-tuning mechanisms both affecting miRNA processing and altering mature miRNA target specificity.

Original publication

DOI

10.1016/j.cell.2013.04.003

Type

Journal article

Journal

Cell

Publication Date

25/04/2013

Volume

153

Pages

516 - 519

Keywords

Animals, Gene Expression Regulation, Humans, MicroRNAs, RNA Processing, Post-Transcriptional, Ribonuclease III